About

Cognito is developing novel and innovative therapeutics designed to potentially improve the lives of patients living with neurodegenerative disease.
cognito vr headset
Cognito's headset design concept
a woman wearing office attirea man wearing office attire
2016
Cognito founders Ed Boyden and Li-Huei Tsai link gamma waves and Alzheimer’s progression

For decades, neurobiologists have been aware that undisrupted gamma wave activity is a measure of brain health and supports key brain processes involved in synaptic and myelin plasticity. Furthermore, this activity is disrupted in neurodegenerative conditions such as Alzheimer’s disease.

During preclinical research at MIT, Ed Boyden and Li-Huei Tsai pushed this knowledge further. They hypothesized that sensory stimulation could evoke gamma activity in Alzheimer’s disease to slow the rate of disease progression. After confirming these observations in preclinical models, they founded Cognito to bring this breakthrough to patients.

cognito vr headset
Cognito's headset design concept
2021
Cognito’s treatment receives FDA Breakthrough Device Designation

Cognito’s treatment was selected for the FDA Breakthrough Device Designation for the treatment of cognitive and functional symptoms associated with Alzheimer’s disease. This designation will help us to reach more patients sooner with our treatment.

woman using the cognito vr headset
Cognito's headset design concept
2023
Cognito announces successful feasibility study results

Patients in our OVERTURE feasibility study experienced 69% slowing of brain volume loss (MRI) and 77% slowing of functional decline (ADCVS-ADL) compared to the control group, without serious treatment-limiting side effects.

Team
Founder
Ed Boyden
Founder
Li-Huei Tsai
Chief Executive Officer
Christian Howell
Chief Medical Officer
Ralph Kern
Chief Business & Financial Officer
Steve Worthy
Chief Clinical & Regulatory Officer
Robbert Zusterzeel
Chief Strategy Officer
Pritesh Shah
PR & Investor Relations
Kimberly Ha
Board of Directors
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Laura Brege

Stephen Bruso

Gerald Chan

Christian Howell

Richard Kuntz

Helen Liang

Jarod Rutledge

Advisory Boards
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Scientific Advisory Board

Claudio Babiloni, PhD

Professor of Physiology
University of Rome

Randy L. Buckner, Ph.D.

Sosland Family Professor of Psychology & Neuroscience
Harvard University & Medical School

Jose Cortes-Briones, Ph.D.

Assistant Professor, Department of Psychiatry
Yale School of Medicine

Mihály Hajós

Professor Adjunct
Yale

Allan Levey

Scientific Advisory
Emory

Bijan Pesaran

Scientific Advisory
UPenn

Annabelle Singer

Scientific Advisory
Georgia Tech

Thomas C. Südhof, M.D.

Avram Goldstein Professor & Investigator
Stanford, Howard Hughes Medical Institute

Kevin J. Tracey

Scientific Advisory
Feinstein Institutes

Hans Wigzell M.D.,Ph.D.

Professor Emeritus in Immunology
Karolinska Institute, Stockholm, Sweden
Medical Advisory Board

Barbara Bendlin

Medical Advisory
University of Wisconsin

Adam Brickman, Ph.D.

Professor of Neuropsychology
Columbia University

Michelle Papka

Medical Advisory
Cognitive Research Center

Anton P. Porsteinsson M.D.

Professor of Psychiatry, Neurology, Neuroscience, & Medicine
University of Rochester School of Medicine & Dentistry

Paul R. Solomon, PhD

Founder and Director
Boston Center for Memory

Henrik Zetterberg

Medical Advisory
University of Gothenburg
Join our team
At Cognito, we’re creating more treatment options for Alzheimer’s patients. Join our team and become a part of our mission.